ZC-B

ZC-B
Clinical data
Other names3-(4-Bromo-2,5-dimethoxyphenyl)azetidine; 2C-B-AZET; 2C-B-Azet
Identifiers
  • 3-(4-bromo-2,5-dimethoxyphenyl)azetidine
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC11H14BrNO2
Molar mass272.142 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1C2CNC2)OC)Br
  • InChI=1S/C11H14BrNO2/c1-14-10-4-9(12)11(15-2)3-8(10)7-5-13-6-7/h3-4,7,13H,5-6H2,1-2H3
  • Key:YFCASESLVDHSAW-UHFFFAOYSA-N

ZC-B, also known as 3-(4-bromo-2,5-dimethoxyphenyl)azetidine or as 2C-B-AZET, is a phenethylamine derivative which acts as a serotonin receptor agonist selective for the 5-HT2 subtypes, with an EC50 of 1.6 nM at 5-HT2A, vs 5.8 nM at 5-HT2C. It is structurally related to the psychedelic phenethylamines 2C-B and DOB, but with the amine side chain conformationally restricted as an azetidine ring.