Teniloxazine

Teniloxazine
Clinical data
Other names	Y-8894
Routes of; administration	Oral
ATC code	None;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 2-{[2-(thiophen-2-ylmethyl)phenoxy]methyl}morpholine;
CAS Number	62473-79-4 ; 62473-80-7 (maleate);
PubChem CID	119114;
ChemSpider	106426 ;
UNII	95Q6WNP25P;
ChEMBL	ChEMBL2105438;
CompTox Dashboard (EPA)	DTXSID10866932 ;
Chemical and physical data
Formula	C16H19NO2S
Molar mass	289.39 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O1CCNCC1COc2ccccc2Cc3sccc3;
	InChI InChI=1S/C16H19NO2S/c1-2-6-16(19-12-14-11-17-7-8-18-14)13(4-1)10-15-5-3-9-20-15/h1-6,9,14,17H,7-8,10-12H2 ; Key:OILWWIVKIDXCIB-UHFFFAOYSA-N ;
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Teniloxazine (Lucelan, Metatone), also known as sufoxazine and sulfoxazine, is a drug which is marketed in Japan. Though initially investigated as a neuroprotective and nootropic agent for the treatment of cerebrovascular insufficiency in the 1980s, it was ultimately developed and approved as an antidepressant instead. It acts as a potent norepinephrine reuptake inhibitor, with fair selectivity over the serotonin and dopamine transporters, and also behaves as an antagonist of the 5-HT_2A receptor.