Norepinephrine reuptake inhibitor

Norepinephrine reuptake inhibitor
Drug class
SynonymsNRI; NERI; Noradrenaline reuptake inhibitor; Adrenergic reuptake inhibitor
External links
MeSHD018759
Legal status
In Wikidata

A norepinephrine reuptake inhibitor (NRI), also known as a noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor, is a type of drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn leads to increased extracellular concentrations of norepinephrine and epinephrine and therefore can increase adrenergic neurotransmission.

A closely related type of drug is a norepinephrine releasing agent (NRA).