Shimon Sakaguchi

Shimon Sakaguchi
坂口 志文
Born (1951-01-19) 19 January 1951
Nagahama, Shiga, Japan
EducationKyoto University (MD, PhD)
Known forRegulatory T cells
AwardsWilliam B. Coley Award (2004)
Canada Gairdner International Award (2015)
Crafoord Prize (2017)
Robert Koch Prize (2020)
Nobel Prize in Physiology or Medicine (2025)
Scientific career
FieldsPathology
Immunology
InstitutionsOsaka University

Shimon Sakaguchi (坂口 志文, Sakaguchi Shimon; born 19 January 1951) is a Japanese immunologist, a Distinguished Professor of Osaka University, and a Professor Emeritus of Kyoto University.

His work includes the discovery of regulatory T cells and describing their role in the immune system. In 2025, he was jointly awarded the Nobel Prize in Physiology or Medicine with Mary E. Brunkow and Fred Ramsdell.

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