Mary E. Brunkow
Mary Elizabeth Brunkow | |
|---|---|
Brunkow at the U.S. Embassy Sweden Nobel Laureate reception. | |
| Born | 1961 (age 64–65) Portland, Oregon, U.S. |
| Education | University of Washington (BS) Princeton University (PhD) |
| Known for | FOXP3 |
| Awards | Nobel Prize in Physiology or Medicine (2025) |
| Scientific career | |
| Fields | Immunology Molecular biology |
| Institutions | Institute for Systems Biology Celltech R&D |
| Thesis | Expression and function of the H19 gene in transgenic mice (1991) |
| Doctoral advisor | Shirley M. Tilghman |
Mary Elizabeth Brunkow (born 1961) is an American molecular biologist, immunologist and Nobel Prize laureate. She is known for co-identifying the gene later named FOXP3 as the cause of the scurfy mouse phenotype, a finding that became foundational for modern regulatory T cell biology.
In 2025, she was jointly awarded the Nobel Prize in Physiology or Medicine with Fred Ramsdell and Shimon Sakaguchi for their work in peripheral immune tolerance.