SUPT5H

SUPT5H
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DO3, 2E6Z, 2E70, 3H7H, 4L1U
Identifiers
Aliases	SUPT5H, SPT5, SPT5H, Tat-CT1, SPT5 homolog, DSIF elongation factor subunit
External IDs	OMIM: 602102; MGI: 1202400; HomoloGene: 2384; GeneCards: SUPT5H; OMA:SUPT5H - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	39,476,670 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	28,038,171 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; anterior pituitary; ; sural nerve; ; right hemisphere of cerebellum; ; right lobe of thyroid gland; ; right uterine tube; ; left lobe of thyroid gland; ; apex of heart; ; right frontal lobe;
	Top expressed in
	adrenal gland; ; Gonadal ridge; ; internal carotid artery; ; external carotid artery; ; fossa; ; crypt of lieberkuhn of small intestine; ; lacrimal gland; ; tail of embryo; ; vestibular membrane of cochlear duct; ; motor neuron;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein heterodimerization activity; enzyme binding; chromatin binding; RNA binding; DNA binding; mRNA binding;
Cellular component	nucleoplasm; DSIF complex; nucleus;
Biological process	chromatin remodeling; negative regulation of mRNA polyadenylation; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter; regulation of DNA-templated transcription, elongation; negative regulation of transcription by RNA polymerase II; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; response to organic substance; transcription, DNA-templated; negative regulation of DNA-templated transcription, elongation; positive regulation of DNA-templated transcription, elongation; positive regulation of macroautophagy; DNA-templated transcription, elongation; single stranded viral RNA replication via double stranded DNA intermediate; positive regulation of viral transcription; cell cycle; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6829
	20924
	ENSG00000196235
	ENSMUSG00000003435
	O00267
	O55201
NM_001111020; NM_001130824; NM_001130825; NM_003169; NM_001319990;
	NM_001319991
	NM_013676
NP_001104490; NP_001124296; NP_001124297; NP_001306919; NP_001306920;
	NP_003160
	NP_038704
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene. Together with hSPT4, it composes DSIF in humans.