SUPT4H1

SUPT4H1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3H7H
Identifiers
Aliases	SUPT4H1, SPT4, SPT4H, SUPT4H, Supt4a, SPT4 homolog, DSIF elongation factor subunit
External IDs	OMIM: 603555; MGI: 107416; HomoloGene: 68303; GeneCards: SUPT4H1; OMA:SUPT4H1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	87,634,449 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; Achilles tendon; ; bone marrow; ; stromal cell of endometrium; ; lymph node; ; islet of Langerhans; ; ganglionic eminence; ; bone marrow cell; ; right adrenal gland;
	Top expressed in
	granulocyte; ; morula; ; embryo; ; embryo; ; yolk sac; ; ventricular zone; ; right kidney; ; neural layer of retina; ; lip; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; zinc ion binding; metal ion binding; protein binding; protein heterodimerization activity; RNA polymerase II complex binding; single-stranded RNA binding;
Cellular component	nucleoplasm; DSIF complex; nucleus;
Biological process	chromatin remodeling; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; negative regulation of transcription elongation from RNA polymerase II promoter; transcription, DNA-templated; negative regulation of DNA-templated transcription, elongation; positive regulation of DNA-templated transcription, elongation; positive regulation of transcription by RNA polymerase II; mRNA processing; regulation of transcription elongation from RNA polymerase II promoter; chromatin organization; positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologs
	6827
	20922
	n/a
	ENSMUSG00000020485
	P63272
	P63271
	NM_003168
	NM_009296; NM_001355753
	NP_003159
	NP_033322; NP_001342682
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription elongation factor SPT4 is a protein that in humans is encoded by the SUPT4H1 gene. Together with hSPT5, it composes DSIF in humans.