Route 1 (Paraguay)

National Route 01
Ruta nacional PY01
Mcal. Francisco Solano López
PY01 highlighted in red
PY01 near Paraguarí
Route information
Maintained by MOPC
Length382 km (237 mi)
StatusOpen
HistoryEstablished 1967; rerouted 2019
Major junctions
North endAsunción
Major intersections PY10 in Paraguarí, PI

PY18 in Carapeguá, PI
PY04 in San Ignacio, MS
PY20 in San Patricio, MS
PY08 in Coronel Bogado, IT

PY06 in Encarnación, IT
South endEncarnación
Location
CountryParaguay
Major citiesVilla Elisa, Paraguarí, San Juan Bautista, San Ignacio, Coronel Bogado
Highway system
National Roads in Paraguay

National Route 1 (officially PY01, Ruta Nacional Número 1), named after Marshal Francisco Solano López, is a national highway in Paraguay running 382 km (237 mi) from the capital Asunción south to Encarnación on the Paraná River. It crosses the departments of Central, Paraguarí, Misiones, and Itapúa. The route begins at the intersection of Choferes del Chaco and Fernando de la Mora Avenues (Cuatro Mojones) in Asunción and ends at the San Roque González de Santa Cruz Bridge over the Paraná.

Paraguay's second-busiest highway after PY02, PY01 connects the Asunción metropolitan area to the Argentine border and carries the bulk of overland freight moving between Paraguay and northeastern Argentina. As of 2025, the route is the subject of a public-private partnership (APP) contract worth more than USD 400 million to duplicate the carriageway between Cuatro Mojones and Quiindy.