Quingestrone

Quingestrone
Clinical data
Trade names	Enol-Luteovis
Other names	W-3399; Progesterone 3-cyclopentyl enol ether; PCPE; 3-Cyclopentyloxypregna-3,5-dien-20-one
Routes of; administration	By mouth
Drug class	Progestogen; Progestin; Progestogen ether; Neurosteroid
ATC code	G03A (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 1-[(8S,9S,10R,13S,14S,17S)-3-cyclopentyloxy-10,13-dimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone;
CAS Number	67-95-8;
PubChem CID	9929903;
ChemSpider	8105534;
UNII	0612VZ9I5Z;
KEGG	D05680;
ChEMBL	ChEMBL2104568;
CompTox Dashboard (EPA)	DTXSID00217196 ;
Chemical and physical data
Formula	C26H38O2
Molar mass	382.588 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(=C4)OC5CCCC5)C)C;
	InChI InChI=1S/C26H38O2/c1-17(27)22-10-11-23-21-9-8-18-16-20(28-19-6-4-5-7-19)12-14-25(18,2)24(21)13-15-26(22,23)3/h8,16,19,21-24H,4-7,9-15H2,1-3H3/t21-,22+,23-,24-,25-,26+/m0/s1; Key:XAVRSHOUEXATJE-FBQZJRKBSA-N;

Quingestrone, also known as progesterone 3-cyclopentyl enol ether (PCPE) and sold under the brand name Enol-Luteovis, is a progestin medication which was previously used in birth control pills in Italy but is now no longer marketed. It is taken by mouth.

Quingestrone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak glucocorticoid activity.

Quingestrone was introduced for medical use by 1962. It is no longer available.