Jewish revolt against Constantius Gallus

The Jewish revolt against Constantius Gallus, also known as the Gallus Revolt, erupted during the Roman civil war of 350–353, upon destabilization across the Roman Empire. In 351–352, the Jews of the Roman province of Syria Palaestina revolted against the rule of Constantius Gallus, brother-in-law of Emperor Constantius II and Caesar of the eastern part of the Roman Empire. The revolt was crushed by Gallus' general Ursicinus.

The rebellion was led by Isaac of Diocaesarea (also known as Isaac of Sepphoris), aided by a certain Patricius and had its epicentre in the town of Diocaesarea (the Greco-Roman referent for Sepphoris). Jerome records that the revolt began with a night attack on the Roman garrison, which was destroyed, and allowed the Jews to procure the necessary weapons. According to the 9th-century author Theophanes the Confessor, the rebels subsequently killed the people of different ethnicities, pagan Greek Hellenes and Samaritans.