HLA-A34

HLA-A34
(MHC Class I, A cell surface antigen)
HLA-A34
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*34--, β2-microglobulin
Older namesA10
Subtypes
Subtype
allele
Available structures
A34.1 *3401
A34.2 *3402
{{{cNick3}}} *34{{{cAllele3}}}
{{{cNick4}}} *34{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A34 (A34) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α34 subset of HLA-A α-chains. For A34, the alpha "A" chain are encoded by the HLA-A*34 allele group and the β-chain are encoded by B2M locus. A34 and A*34 are almost synonymous in meaning. A34 is a split antigen of the broad antigen serotype A10. A34 is a sister serotype of A25, A26, A43, and A66.

Further information: History and naming of human leukocyte antigens

A34 is most similar to A66.

Serotype

A34 recognition of some HLA A*34 gene products
A*34 A34 A10 Sample
allele % % size (N)
*3401 67 5 269
*3402 89 2 996

A34 serotyping is modest.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.