HLA-A32

HLA-A32
HLA-A32
(MHC Class I, A cell surface antigen)
	HLA-A32
About
Protein	transmembrane receptor/ligand
Structure	αβ heterodimer
Subunits	HLA-A*3201, β2-microglobulin
Older names	"A19"
Subtypes
Subtype
Subtype	allele
A19	*3201
{{{cNick2}}}	*32{{{cAllele2}}}
{{{cNick3}}}	*32{{{cAllele3}}}
{{{cNick4}}}	*32{{{cAllele4}}}
	Alleles link-out to IMGT/HLA database at EBI

HLA-A32 (A32) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α³² subset of HLA-A α-chains. For A32, the alpha "A" chain are encoded by the HLA-A*32 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*3201. A32 and A*32 are almost synonymous in meaning. A32 is a split antigen of the broad antigen serotype A19. A32 is a sister serotype of A29, A30, A31, A33, and A74.

Serotype

A32 recognition of some HLA A*32 gene products
A*32	A32	Sample
allele	%	size (N)
*3201	94	3441

A32 Serotyping efficiency for the predominant allele is good. There are 16 known alleles that result in 15 isoforms of HLA-A32. One isoform may be poorly expressed..