Dimefadane

Dimefadane
Clinical data
Other namesSK&F 1340, SKF 1340, NIH 7661,
Identifiers
  • N,N-dimethyl-3-phenyl-2,3-dihydro-1H-inden-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H19N
Molar mass237.346 g·mol−1
3D model (JSmol)
  • CN(C)C1CC(C2=CC=CC=C12)C3=CC=CC=C3
  • InChI=1S/C17H19N/c1-18(2)17-12-16(13-8-4-3-5-9-13)14-10-6-7-11-15(14)17/h3-11,16-17H,12H2,1-2H3
  • Key:GAVBHVRHVQMWEI-UHFFFAOYSA-N

Dimefadane is an analgesic agent with about the same activity as codeine, but without any of the GI side effects. Although it does not adhere to the classical morphine rule (structure includes a tertiary amine, phenyl ring and quaternary carbon), it is not known if this is opioidergic. It has structure activity relationships that can be compared to tametraline. Klaus Bøgesø used dimefadane as the harbinger to Indatraline.