Indatraline

Indatraline
Clinical data
Other namesLu 19-005
Routes of
administration
By mouth
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H15Cl2N
Molar mass292.20 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1Cl)[C@@H]3C[C@H](NC)c2ccccc23
  • InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16-/m0/s1 Y
  • Key:SVFXPTLYMIXFRX-BBRMVZONSA-N Y
  (verify)

Indatraline hydrochloride (Lu 19-005) is an antidepressive agent and non-selective monoamine transporter inhibitor that blocks the reuptake of dopamine, norepinephrine, and serotonin with similar efficacy to cocaine. This compound may be used to treat cocaine addictions as its effects have a slower onset and a longer duration than those of cocaine. Indatraline has been shown to block the action of methamphetamine and MDMA in laboratory experiments.