Glutathione dehydrogenase (ascorbate)
Glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) is an enzyme that catalyzes the chemical reaction
The substrates of this enzyme are dehydroascorbic acid and glutathione. Its products are glutathione disulfide and ascorbic acid (vitamin C).
| Glutathione dehydrogenase (ascorbate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Dehydroascorbate reductase, Pennisetum americanum | |||||||||
| Identifiers | |||||||||
| EC no. | 1.8.5.1 | ||||||||
| CAS no. | 9026-38-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a quinone or similar compound as acceptor. The systematic name of this enzyme class is glutathione:dehydroascorbate oxidoreductase. Other names in common use include dehydroascorbic reductase, dehydroascorbic acid reductase, glutathione dehydroascorbate reductase, DHA reductase, dehydroascorbate reductase, GDOR, and glutathione:dehydroascorbic acid oxidoreductase. This enzyme participates in three metabolic pathways: ascorbate and aldarate metabolism, glutamate metabolism, and glutathione metabolism.