Glutathione

Glutathione
Names
	IUPAC name γ-Glutamylcysteinylglycine
	Systematic IUPAC name (2S)-2-Amino-5-({(2R)-1-[(carboxymethyl)amino]-1-oxo-3-sulfanylpropan-2-yl}amino)-5-oxopentanoic acid
	Other names γ-L-Glutamyl-L-cysteinylglycine; (2S)-2-Amino-4-({(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid
Identifiers
CAS Number	70-18-8 ;
3D model (JSmol)	Interactive image;
Abbreviations	GSH
ChEBI	CHEBI:16856 ;
ChEMBL	ChEMBL1543 ;
ChemSpider	111188 ;
DrugBank	DB00143 ;
ECHA InfoCard	100.000.660
IUPHAR/BPS	6737;
KEGG	C00051 ;
MeSH	Glutathione
PubChem CID	124886;
UNII	GAN16C9B8O ;
CompTox Dashboard (EPA)	DTXSID6023101 ;
	InChI InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 Key: RWSXRVCMGQZWBV-WDSKDSINSA-N ;
	SMILES C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N;
Properties
Chemical formula	C10H17N3O6S
Molar mass	307.32 g·mol−1
Melting point	195 °C (383 °F; 468 K)
Solubility in water	Freely soluble
Solubility in methanol, diethyl ether	Insoluble
Pharmacology
ATC code	V03AB32 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Glutathione (GSH, /ˌɡluːtəˈθaɪoʊn/) is a tripeptide made of the amino acids glutamate, cysteine, and glycine. It is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals.

It is synthesized by attaching cysteine to the carboxyl group of the glutamate side chain with a gamma peptide linkage, and to glycine with a normal peptide linkage.