Anti-Müllerian hormone type-2 receptor

AMHR2
Identifiers
Aliases	AMHR2, AMHR, MISR2, MISRII, MRII, anti-Mullerian hormone receptor type 2
External IDs	OMIM: 600956; MGI: 105062; HomoloGene: 10746; GeneCards: AMHR2; OMA:AMHR2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,431,672 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,363,068 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; left ovary; ; right ovary; ; left testis; ; body of pancreas; ; right testis; ; skeletal muscle tissue; ; spleen;
	Top expressed in
	seminiferous tubule; ; spermatocyte; ; facial motor nucleus; ; ovary; ; muscle layer of urethra; ; Gonadal ridge; ; epithelium of urethra; ; epithelium of female urethra; ; soleus muscle; ; lamina propria of vagina;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; hormone binding; transforming growth factor beta receptor activity, type II; metal ion binding; kinase activity; protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; protein binding; ATP binding; anti-Mullerian hormone receptor activity; transforming growth factor beta-activated receptor activity; growth factor binding; SMAD binding;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; plasma membrane; receptor complex;
Biological process	male gonad development; phosphorylation; sex differentiation; female gonad development; negative regulation of anti-Mullerian hormone signaling pathway; Mullerian duct regression; protein phosphorylation; transmembrane receptor protein serine/threonine kinase signaling pathway; transforming growth factor beta receptor signaling pathway; BMP signaling pathway; anti-Mullerian hormone signaling pathway; pattern specification process;
	Sources:Amigo / QuickGO
Orthologs
	269
	110542
	ENSG00000135409
	ENSMUSG00000023047
	Q16671
	Q8K592
	NM_001164690; NM_001164691; NM_020547
	NM_144547; NM_001356575
	NP_001158162; NP_001158163; NP_065434
	NP_653130; NP_001343504
	Wikidata
View/Edit Human	View/Edit Mouse

Anti-Muellerian hormone type-2 receptor (AMHR2), also known as Müllerian inhibiting substance type II receptor (MISRII), is a receptor for anti-Müllerian hormone (AMH). It is a protein in humans that is encoded by the AMHR2 gene. AMHR2 protein plays a role in male sex differentiation and the formation of ovarian follicles.