25B-NBOMe

25B-NBOMe
Clinical data
Other namesNBOMe-2C-B; Cimbi-36; Nova; BOM 2-CB; N-(2-Methoxybenzyl)-4-bromo-2,5-dimethoxyphenethylamine
Routes of
administration
Sublingual, buccal, intranasal
Drug classSerotonin 5-HT2 receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Metabolites5-DM-25B-NBOMe
Onset of action45–75 minutes or 15–120 minutes
Duration of action8–12 hours
Identifiers
  • 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H22BrNO3
Molar mass380.282 g·mol−1
3D model (JSmol)
  • COC1=CC=CC=C1CNCCC2=CC(=C(C=C2OC)Br)OC
  • InChI=1S/C18H22BrNO3/c1-21-16-7-5-4-6-14(16)12-20-9-8-13-10-18(23-3)15(19)11-17(13)22-2/h4-7,10-11,20H,8-9,12H2,1-3H3 Y
  • Key:SUXGNJVVBGJEFB-UHFFFAOYSA-N Y
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25B-NBOMe, also known as NBOMe-2C-B, Cimbi-36, or as N-(2-methoxybenzyl)-4-bromo-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine, 2C, and 25-NB (NBOMe) families. It is the N-(2-methoxybenzyl) derivative of 2C-B. The drug is taken sublingually, bucally, or intranasally.

It acts as a potent full agonist for the serotonin 5-HT2A receptor.

25B-NBOMe was first described in the scientific literature by Ralf Heim and colleagues at the Free University of Berlin by 1999. After 25I-NBOMe and along with 25C-NBOMe, 25B-NBOMe is one of the most widely used 25-NB psychedelics.