ZNF555

ZNF555
Identifiers
Aliases	ZNF555, zinc finger protein 555
External IDs	HomoloGene: 65060; GeneCards: ZNF555; OMA:ZNF555 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	2,860,471 bp
RNA expression pattern
	Top expressed in
	amniotic fluid; ; secondary oocyte; ; sperm; ; gonad; ; buccal mucosa cell; ; testicle; ; cartilage tissue; ; ventricular zone; ; ganglionic eminence; ; islet of Langerhans;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	148254
	n/a
	ENSG00000186300
	n/a
	Q8NEP9
	n/a
	NM_001172775; NM_152791
	n/a
	NP_001166246; NP_690004
	n/a
	Wikidata
View/Edit Human

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Zinc finger protein 555 (ZNF555) protein encoded by the ZNF555 gene. It is located on the short arm (19p13.3 ) of the human chromosome 19 (hg38) at position chr19:2,841,573-2,853,952, spanning 12,380 base pairs. It contains four coding exons.

It belongs to the Krüppel associated box (KRAB) C2H2 zinc-finger family and is predicted to act as a sequence-specific transcriptional regulator. Experimental work in human myoblasts suggests that ZNF555 can bind a 4qA-subtelomeric enhancer and modulate expression of the mitochondrial ADP/ATP translocase gene SLC25A4 (ANT1), implicating it in mechanisms proposed for facioscapulohumeral muscular dystrophy (FSHD).