Y box binding protein 1

YBX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1H95
Identifiers
Aliases	YBX1, BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1, CBF-A, EFI-A, Y-box binding protein 1
External IDs	OMIM: 154030; MGI: 99146; HomoloGene: 88707; GeneCards: YBX1; OMA:YBX1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	42,703,805 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	119,151,801 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; ganglionic eminence; ; ventricular zone; ; Achilles tendon; ; gastrocnemius muscle; ; muscle of thigh; ; skeletal muscle tissue; ; left ventricle; ; stromal cell of endometrium;
	Top expressed in
	Ileal epithelium; ; primitive streak; ; tail of embryo; ; abdominal wall; ; medial ganglionic eminence; ; endothelial cell of lymphatic vessel; ; seminiferous tubule; ; choroid plexus of fourth ventricle; ; migratory enteric neural crest cell; ; maxillary prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; RNA binding; nucleic acid binding; GTPase binding; double-stranded DNA binding; single-stranded DNA binding; chromatin binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; CRD-mediated mRNA stability complex; nuclear membrane; intracellular membrane-bounded organelle; U12-type spliceosomal complex; nucleoplasm; extracellular region; cytoplasmic stress granule; extracellular exosome; nucleus; histone pre-mRNA 3'end processing complex; cytosol; ribonucleoprotein complex;
Biological process	CRD-mediated mRNA stabilization; mRNA splicing, via spliceosome; regulation of transcription, DNA-templated; mRNA processing; transcription by RNA polymerase II; protein localization to cytoplasmic stress granule; transcription, DNA-templated; positive regulation of cell division; positive regulation of transcription by RNA polymerase II; in utero embryonic development; RNA splicing; negative regulation of striated muscle cell differentiation; negative regulation of transcription by RNA polymerase II; Notch signaling pathway; cellular response to interleukin-7;
	Sources:Amigo / QuickGO
Orthologs
	4904
	22608
	ENSG00000065978
	ENSMUSG00000028639
	P67809
	P62960
	NM_004559
	NM_011732
	NP_004550
	NP_035862
	Wikidata
View/Edit Human	View/Edit Mouse

Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene. YBX1 is an RNA binding protein that stabilises messenger RNAs modified with N6-methyladenosine.