WWOX

WWOX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WMV
Identifiers
Aliases	WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28
External IDs	OMIM: 605131; MGI: 1931237; HomoloGene: 56334; GeneCards: WWOX; OMA:WWOX - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	79,212,667 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	116,079,447 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; optic nerve; ; glomerulus; ; sural nerve; ; metanephric glomerulus; ; Epithelium of choroid plexus; ; pars reticulata; ; endothelial cell; ; kidney tubule; ; pars compacta;
	Top expressed in
	interventricular septum; ; neural layer of retina; ; zygote; ; amygdala; ; visual cortex; ; cerebellar cortex; ; secondary oocyte; ; primary visual cortex; ; spermatocyte; ; lens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; protein dimerization activity; protein binding; enzyme binding; oxidoreductase activity;
Cellular component	cytoplasm; cytosol; Golgi apparatus; plasma membrane; microvillus; RNA polymerase II transcription regulator complex; mitochondrion; nucleus;
Biological process	cellular response to transforming growth factor beta stimulus; steroid metabolic process; extrinsic apoptotic signaling pathway; negative regulation of Wnt signaling pathway; skeletal system morphogenesis; Wnt signaling pathway; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; osteoblast differentiation; intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of transcription by RNA polymerase II; apoptotic process; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	51741
	80707
	ENSG00000186153
	ENSMUSG00000004637
	Q9NZC7
	Q91WL8
NM_001291997; NM_016373; NM_018560; NM_130788; NM_130790;
	NM_130791; NM_130792; NM_130844
	NM_019573
	NP_001278926; NP_057457; NP_570607
	NP_062519
	Wikidata
View/Edit Human	View/Edit Mouse

WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene.