WD40 repeat
| WD domain, G-beta repeat | |||||||
|---|---|---|---|---|---|---|---|
Ribbon diagram of the C-terminal WD40 domain of Tup1 (a transcriptional corepressor in yeast), which adopts a 7-bladed beta-propeller fold. Ribbon is colored from blue (N-terminus) to red (C-terminus). | |||||||
| Identifiers | |||||||
| Symbol | WD40 | ||||||
| Pfam | PF00400 | ||||||
| Pfam clan | CL0186 | ||||||
| InterPro | IPR001680 | ||||||
| PROSITE | PDOC00574 | ||||||
| SCOP2 | 1gp2 / SCOPe / SUPFAM | ||||||
| CDD | cd00200 | ||||||
| |||||||
The WD40 repeat (also known as the WD or beta-transducin repeat) is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Tandem copies of these repeats typically fold together to form a type of circular solenoid protein domain called the WD40 domain.