Vaccination policy of the United States

Vaccination policy of the United States is the subset of U.S. federal health policy that deals with immunization against infectious disease. It is decided at various levels of the government, including the individual states. This policy has been developed over the approximately two centuries since the invention of vaccination with the purpose of eradicating disease from the U.S. population, or creating a herd immunity. Policies intended to encourage vaccination impact numerous areas of law, including regulation of vaccine safety, funding of vaccination programs, vaccine mandates, adverse event reporting requirements, and compensation for injuries asserted to be associated with vaccination.

The Advisory Committee on Immunization Practices (ACIP) is responsible for making vaccine policies and recommendations for the vaccination schedule used in the United States. As of June 2025, after Secretary of Health and Human Services Robert F. Kennedy Jr. fired all 17 ACIP members and replaced them, the new members are either anti-vaccine activists or lack expertise with vaccines. The resulting lack of trust in future changes to vaccine recommendations resulted in the creation of two interstate collaborations, the West Coast Health Alliance and Northeast Public Health Collaborative.