VP40

VP40
VP40 matrix protein hexamer, Ebola virus
Identifiers
SymbolVP40
PfamPF07447
InterProIPR008986
SCOP21h2c / SCOPe / SUPFAM
Available protein structures:
PDB  IPR008986 PF07447 (ECOD; PDBsum)  
AlphaFold

In molecular biology, VP40 is the name of a viral matrix protein. Most commonly, it is found in the Ebola virus (EBOV), a type of non-segmented, negative-strand RNA virus. Ebola virus causes a severe and often fatal haemorrhagic fever in humans, known as Ebola virus disease. The virus matrix protein VP40 is a major structural protein that plays a central role in virus assembly and budding at the plasma membrane of infected cells.