VP40
| VP40 | |||||||
|---|---|---|---|---|---|---|---|
VP40 matrix protein hexamer, Ebola virus | |||||||
| Identifiers | |||||||
| Symbol | VP40 | ||||||
| Pfam | PF07447 | ||||||
| InterPro | IPR008986 | ||||||
| SCOP2 | 1h2c / SCOPe / SUPFAM | ||||||
| |||||||
In molecular biology, VP40 is the name of a viral matrix protein. Most commonly, it is found in the Ebola virus (EBOV), a type of non-segmented, negative-strand RNA virus. Ebola virus causes a severe and often fatal haemorrhagic fever in humans, known as Ebola virus disease. The virus matrix protein VP40 is a major structural protein that plays a central role in virus assembly and budding at the plasma membrane of infected cells.