| C51 |
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| System | Metrobus |
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| Operator | Washington Metropolitan Area Transit Authority |
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| Garage | Shepherd Parkway |
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| Livery | Local |
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| Status | In service |
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| Began service | 1922 as a streetcar route C51: June 29, 2025 |
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| Ended service | 96: June 29, 2025 |
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| Predecessors | 40, 42, and 44 |
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| Locale | Northwest, Northeast, Southeast |
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| Communities served | Tenleytown, Cathedral Heights, McLean Gardens, Cleveland Park, Woodley Park, Adams Morgan, Lanier Heights, Cardozo, LeDroit Park, Truxton Circle, Capitol Hill, Stanton Park, Kingman Park, Hill East, Navy Yard, Anacostia |
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| Landmarks served | Anacostia station, Potomac Avenue station, Stadium-Armory station, Washington Union Station, Union Station, U Street station, Reeves Center, Adams Morgan, Duke Ellington Bridge, Woodley Park station, Washington National Cathedral, Tenleytown station |
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| Start | Tenleytown station |
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| Via | Potomac Avenue SE, Massachusetts Avenue SE/NE, New Jersey Avenue NW, U Street NW, Wisconsin Avenue NW |
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| End | Anacostia station |
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| Length | 70 minutes |
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| Other routes | C53 |
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| Level | Daily |
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| Frequency | 20 minutes |
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| Operates | Mon-Sat: 4:30 AM - 11:00 PM Sun: 5:00 AM - 11:00 PM |
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| Ridership | 96: 1,455,146 (FY 2024) |
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| Transfers | SmarTrip only |
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| ← C43 |
{{{system_nav}}} |
C53 → |
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The U Street–Anacostia Line, designated Route C51, is a daily bus route operated by the Washington Metropolitan Area Transit Authority between Tenleytown station of the Red Line of the Washington Metro and Anacostia station of the Green Line of the Washington Metro. This route replaced former routes 96 and 97 on the East Capitol Street–Cardozo Line on June 29, 2025. The line operates every 20 minutes at all times and trips take roughly 80 minutes to complete.