UPS Airlines Flight 2976

UPS Airlines Flight 2976
Aerial view of the crash site
Accident
DateNovember 4, 2025
SummaryCrashed shortly after takeoff following left engine detachment due to pylon failure, under investigation
Site
Total fatalities15
Total injuries22
Aircraft

N259UP, the aircraft involved in the accident, pictured in April 2025
Aircraft typeMcDonnell Douglas MD-11F
OperatorUPS Airlines
IATA flight No.5X2976
ICAO flight No.UPS2976
Call signUPS 2976
RegistrationN259UP
Flight originLouisville Muhammad Ali International Airport, Louisville, Kentucky, U.S.
DestinationDaniel K. Inouye International Airport, Honolulu, Hawaii, U.S.
Occupants3
Crew3
Fatalities3
Survivors0
Ground casualties
Ground fatalities12
Ground injuries22

UPS Airlines Flight 2976 was a scheduled domestic cargo flight in the United States from Louisville Muhammad Ali International Airport in Louisville, Kentucky, to Honolulu, Hawaii. On November 4, 2025, the McDonnell Douglas MD-11 operating the flight suffered a separation of its left engine during its takeoff roll and crashed into an industrial area seconds after liftoff from the runway, at about 5:13 p.m. local time (22:13 UTC). The crash killed all three crew members on board the aircraft and an additional twelve people on the ground, one of whom succumbed to their injuries on December 25.

The accident is being investigated by the National Transportation Safety Board. Following the accident, UPS retired its remaining MD-11 fleet in January 2026.