UNC13B

UNC13B
Identifiers
Aliases	UNC13B, MUNC13, UNC13, Unc13h2, unc-13 homolog B (C. elegans), unc-13 homolog B, munc13-2
External IDs	OMIM: 605836; MGI: 1342278; HomoloGene: 31376; GeneCards: UNC13B; OMA:UNC13B - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	35,405,338 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	43,264,871 bp
RNA expression pattern
	Top expressed in
	right lung; ; pancreatic ductal cell; ; lower lobe of lung; ; retinal pigment epithelium; ; sperm; ; upper lobe of lung; ; upper lobe of left lung; ; palpebral conjunctiva; ; seminal vesicula; ; epithelium of esophagus;
	Top expressed in
	submandibular gland; ; neural layer of retina; ; lacrimal gland; ; saccule; ; epithelium of lens; ; pineal gland; ; secondary oocyte; ; lobe of prostate; ; parotid gland; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; calmodulin binding; diacylglycerol binding; GTP-dependent protein binding; calcium ion binding; phospholipid binding; syntaxin-1 binding;
Cellular component	cytosol; neuromuscular junction; plasma membrane; synapse; cell junction; cytoplasm; Golgi apparatus; membrane; early phagosome; terminal bouton; calyx of Held; presynaptic active zone; ribbon synapse; presynapse; hippocampal mossy fiber to CA3 synapse; glutamatergic synapse; synaptic vesicle membrane; presynaptic membrane; presynaptic active zone cytoplasmic component;
Biological process	exocytosis; intracellular signal transduction; synaptic vesicle docking; positive regulation of synaptic vesicle priming; synaptic transmission, glutamatergic; regulation of short-term neuronal synaptic plasticity; positive regulation of inhibitory postsynaptic potential; neuromuscular junction development; synaptic vesicle priming; innervation; chemical synaptic transmission; synaptic vesicle exocytosis; negative regulation of synaptic plasticity; positive regulation of apoptotic process; positive regulation of protein secretion; cellular response to glucose stimulus; phagosome maturation; positive regulation of defense response to bacterium; presynaptic dense core vesicle exocytosis; synaptic vesicle maturation; dense core granule priming; neurotransmitter secretion; glutamate secretion; acrosomal vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	10497
	22249
	ENSG00000198722
	ENSMUSG00000028456
	O14795
	Q9Z1N9
NM_006377; NM_001330653; NM_001371186; NM_001371187; NM_001371188;
	NM_001371189; NM_001387551; NM_001387553; NM_001387554; NM_001387555
	NM_001081413; NM_021468; NM_001310758
NP_001317582; NP_006368; NP_001358115; NP_001358116; NP_001358117;
	NP_001358118
	NP_001074882; NP_001297687; NP_067443; NP_001371035
	Wikidata
View/Edit Human	View/Edit Mouse

Protein unc-13 homolog B is a protein that in humans is encoded by the UNC13B gene and in mice by the Munc13-2 gene