UBE2I

UBE2I
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A3S, 1KPS, 1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2O25, 2PE6, 2PX9, 2XWU, 3A4S, 3UIN, 3UIO, 3UIP, 4Y1L, 4W5V, 2VRR, 5D2M, 5F6D, 5F6U, 5F6W, 5F6E, 5F6X, 5F6V, 5F6Y
Identifiers
Aliases	UBE2I, C358B7.1, P18, UBC9, ubiquitin conjugating enzyme E2 I
External IDs	OMIM: 601661; MGI: 107365; HomoloGene: 5574; GeneCards: UBE2I; OMA:UBE2I - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,327,018 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	25,493,596 bp
RNA expression pattern
	Top expressed in
	oocyte; ; ganglionic eminence; ; left ovary; ; ventricular zone; ; monocyte; ; right ovary; ; thymus; ; stromal cell of endometrium; ; left uterine tube; ; left adrenal gland;
	Top expressed in
	zygote; ; tail of embryo; ; genital tubercle; ; ventricular zone; ; embryo; ; spermatid; ; spermatocyte; ; yolk sac; ; embryo; ; lip;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; SUMO transferase activity; ubiquitin protein ligase activity; transcription factor binding; RING-like zinc finger domain binding; HLH domain binding; protein binding; enzyme binding; SUMO conjugating enzyme activity; ATP binding; ubiquitin protein ligase binding; transferase activity; RNA binding; small protein activating enzyme binding; ubiquitin-protein transferase activity; protein C-terminus binding; bHLH transcription factor binding;
Cellular component	cytoplasm; PML body; nuclear body; nucleoplasm; transferase complex; synaptonemal complex; nucleus; cytosol; sumoylated E2 ligase complex; fibrillar center; nuclear envelope; dendrite; synapse;
Biological process	ubiquitin-dependent protein catabolic process; chromosome segregation; protein sumoylation; cell division; global genome nucleotide-excision repair; positive regulation of I-kappaB kinase/NF-kappaB signaling; cell cycle; positive regulation of SUMO transferase activity; viral process; negative regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; regulation of signaling receptor activity; protein ubiquitination; positive regulation of intracellular steroid hormone receptor signaling pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; positive regulation of DNA-binding transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	7329
	22196
	ENSG00000103275
	ENSMUSG00000015120
	P63279
	P63280
	NM_003345; NM_194259; NM_194260; NM_194261
	NM_001177609; NM_001177610; NM_011665; NM_001357694
	NP_003336; NP_919235; NP_919236; NP_919237
	NP_001171080; NP_001171081; NP_035795; NP_001344623
	Wikidata
View/Edit Human	View/Edit Mouse

SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene. It is also sometimes referred to as "ubiquitin conjugating enzyme E2I" or "ubiquitin carrier protein 9", even though these names do not accurately describe its function.