UBE2D2

UBE2D2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UR6, 1W4U, 2CLW, 2ESK, 2ESO, 2ESP, 2ESQ, 3A33, 3JVZ, 3JW0, 3L1Y, 3TGD, 3ZNI, 4A49, 4A4B, 4A4C, 4AUQ, 4DDG, 4LDT, 4V3K, 4V3L, 4WZ3, 5D1L, 5D1K, 5D0M, 5D0K, 5D1M, 5EDV
Identifiers
Aliases	UBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ubiquitin conjugating enzyme E2 D2
External IDs	OMIM: 602962; MGI: 1930715; HomoloGene: 2506; GeneCards: UBE2D2; OMA:UBE2D2 - orthologs
EC number	2.3.2.24
Gene location (Human)
Chr.	Chromosome 5 (human)
End	139,628,434 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	35,942,547 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; right testis; ; left testis; ; right uterine tube; ; gastrocnemius muscle; ; granulocyte; ; sperm; ; rectum; ; tibial arteries;
	Top expressed in
	Gonadal ridge; ; ventral tegmental area; ; external carotid artery; ; dorsomedial hypothalamic nucleus; ; pineal gland; ; mammillary body; ; paraventricular nucleus of hypothalamus; ; human fetus; ; median eminence; ; dorsal tegmental nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; ubiquitin-protein transferase activity; protein binding; ATP binding; ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding;
Cellular component	cytosol; ubiquitin ligase complex; nucleoplasm; extracellular exosome; protein-containing complex;
Biological process	ubiquitin-dependent protein catabolic process; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; Fc-epsilon receptor signaling pathway; protein K48-linked ubiquitination; regulation of transcription from RNA polymerase II promoter in response to hypoxia; T cell receptor signaling pathway; protein autoubiquitination; protein ubiquitination; MyD88-independent toll-like receptor signaling pathway; protein targeting to peroxisome; protein K11-linked ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	7322
	56550
	ENSG00000131508
	ENSMUSG00000091896
	P62837
	P62838
	NM_003339; NM_181838
	NM_019912
	NP_003330; NP_862821
	NP_064296
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the UBE2D2 gene.