U.S. Route 72

U.S. Route 72
U.S. Route 72
Corridor V
	US 72 highlighted in red
Route information
Length	317.811 mi (511.467 km)
Existed	1926–present
Major junctions
West end	US 51 / US 64 / US 70 / US 79 in Memphis, TN
	I-240 at Memphis, TN; I-269 at Collierville, TN; US 45 at Corinth, MS; ; US 43 / US 72 Alt. / SR 17 / SR 20 in Muscle Shoals, AL; I-65 in Athens, AL; US 231 / US 431 in Huntsville, AL; I-565 in Huntsville, AL; I-24 / US 64 in Kimball, TN; US 41 / SR 28 in Jasper, TN; I-24 in Chattanooga, TN;
East end	US 41 / US 76 in Chattanooga, TN
Location
Country	United States
States	Tennessee, Mississippi, Alabama
Counties	TN: Shelby, Fayette; MS: Marshall, Benton, Tippah, Alcorn, Tishomingo; AL: Colbert, Lauderdale, Limestone, Madison, Jackson; TN: Marion, Hamilton
Highway system
	United States Numbered Highway System; List; Special; Divided;
	Tennessee State Routes; Interstate; US; State;
	Mississippi State Highway System; Interstate; US; State;
	Alabama State Highway System; Interstate; US; State;

U.S. Route 72 (US 72) is an east–west United States highway that travels for 317.811 miles (511.467 km) from southwestern Tennessee, throughout North Mississippi, North Alabama, and southeastern Tennessee. The highway's western terminus is in Memphis, Tennessee and its eastern terminus is in Chattanooga. It is the only U.S. Highway to begin and end in the same state, yet pass through other states in between. Prior to the U.S. Highway system signage being posted in 1926, the section eastward from Corinth, Mississippi (covering nearly three quarters of the route) was part of the Lee Highway.