Toxidrome
| Symptoms | BP | HR | RR | Temp | Pupil size | Bowel sounds | Diaphoresis |
|---|---|---|---|---|---|---|---|
| anticholinergic | up | up | up | up | up | down | down |
| cholinergic | ~ | ~ | ~ | ~ | down | up | up |
| hallucinogenic | up | up | up | ~ | up | up | ~ |
| sympathomimetic | up | up | up | up | up | up | up |
| sedative-hypnotic | down | down | down | down | ~ | down | down |
A toxidrome (a portmanteau of toxic and syndrome, coined in 1970 by Mofenson and Greensher) is a syndrome caused by a dangerous level of toxins in the body. It is often the consequence of a drug overdose. Common symptoms include dizziness, disorientation, nausea, vomiting and oscillopsia. It may indicate a medical emergency requiring treatment at a poison control center. Aside from poisoning, a systemic infection may also lead to one. Classic toxidromes may be variable or obscured by co-ingestion of multiple drugs.
A common tool for assessing for the presence of toxidrome in the United Kingdom is the CRESS tool.