The Second Best Hospital in the Galaxy

*The Second Best Hospital in the Galaxy*
The Second Best Hospital in the Galaxy
Genre	Science fiction comedy; Medical drama; Adult animation
Created by	Cirocco Dunlap
Showrunner	Cirocco Dunlap
Voices of	Kieran Culkin; Stephanie Hsu; Natasha Lyonne; Keke Palmer; Maya Rudolph; Sam Smith;
Country of origin	United States
Original language	English
No. of seasons	2
No. of episodes	16
Production
Executive producers	Cirocco Dunlap; Maya Rudolph; Natasha Lyonne; Danielle Renfrew Behrens; Shauna McGarry; Shannon Prynoski; Chris Prynoski; Antonio Canobbio; Ben Kalina;
Producer	Asha Michelle Wilson
Production companies	Amazon MGM Studios; Animal Pictures; Titmouse, Inc.;
Original release
Network	Amazon Prime Video
Release	February 23, 2024 – present
	Infobox instructions (only shown in preview)

The Second Best Hospital in the Galaxy is an American adult animated science fiction comedy series created by Cirocco Dunlap for the streaming service Amazon Prime Video. The series centers on two intergalactic surgeons and best friends as they treat illnesses throughout the galaxy, and was produced by Amazon MGM Studios, Animal Pictures, and Titmouse, Inc., with Dunlap as showrunner.

The series stars the voices of Kieran Culkin, Stephanie Hsu, Natasha Lyonne, Keke Palmer, Maya Rudolph, Sam Smith, Andrew Dismukes, Gary Anthony Williams, and Lennon Parham. Dunlap first conceived the series after wondering how it would be if there were people who could treat the ailments of characters in science-fiction movies. The series was announced in 2022, with Rudolph and Lyonne also set to executive produce. The series draws heavy inspiration from Dunlap's personal life, particularly in its depiction of anxiety. Animation services were provided by Titmouse, Inc.

The Second Best Hospital in the Galaxy premiered on Amazon Prime Video in February 23, 2024, to a generally positive reception. A second season was released on May 27, 2025.