The Calcutta Chromosome

The Calcutta Chromosome
First edition
AuthorAmitav Ghosh
Cover artistShamshad Husain
LanguageEnglish
GenreThriller, speculative fiction
PublisherRavi Dayal
Publication date
1996
Publication placeIndia
Media typePrint (Hardback, later Paperback)
Pages256
ISBN81-7530-005-1
OCLC35759000

The Calcutta Chromosome is a 1996 English-language novel by Indian author Amitav Ghosh. The book, set in Calcutta and New York City at some unspecified time in the future, is a medical thriller that dramatizes the adventures of people who are brought together by a mysterious turn of events. The book is loosely based on the life and times of Sir Ronald Ross, the Nobel Prize–winning scientist who achieved a breakthrough in malaria research in 1898. The novel was the recipient of the Arthur C. Clarke Award in 1997.

Ghosh employs a factual background for the invented events in the novel, drawing upon Ross's Memoirs which were published in 1923.