Tetrahydropyridinylpyrrolopyridine

Tetrahydropyridinylpyrrolopyridines are a group of pyrrolopyridine–tetrahydropyridine derivatives related to the tryptamines. They are not tryptamines themselves, as they feature a pyrrolopyridine instead of indole ring system. The compounds include (R)-69, (R)-70, and CP-94253. They are known to act as serotonin receptor agonists, including of the serotonin 5-HT1 and/or 5-HT2 receptors. Some tetrahydropyridinylpyrrolopyridines, such as (R)-69 and (R)-70, were discovered by Bryan L. Roth and colleagues via ultra-large-scale docking.

Chemical structures of selected tetrahydropyridinylpyrrolopyridines
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