Tetrahydrocannabivarin

Tetrahydrocannabivarin
Clinical data
Routes of; administration	Oral, smoked, inhaled
ATC code	None;
Legal status
Legal status	US: Unscheduled; Also legal in UK, Canada and Netherlands;
Identifiers
	IUPAC name 6,6,9-Trimethyl-3-propyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol;
CAS Number	31262-37-0 ;
PubChem CID	34180;
IUPHAR/BPS	6418;
ChemSpider	31500 ;
UNII	I5YE3I47D8;
CompTox Dashboard (EPA)	DTXSID50950920 ;
Chemical and physical data
Formula	C19H26O2
Molar mass	286.415 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCC1=CC2=C(C3C=C(CCC3C(O2)(C)C)C)C(=C1)O;
	InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 ; Key:ZROLHBHDLIHEMS-HUUCEWRRSA-N ;
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Tetrahydrocannabivarin (THCV, THV, O-4394, GWP42004) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain instead of pentyl (5-carbon), making it non-psychoactive in lower doses. It has been shown to exhibit neuroprotective activity, appetite suppression, glycemic control and reduced side effects compared to THC, making it a potential treatment for management of obesity and diabetes. THCV was studied by Roger Adams as early as 1942.

THCV is prevalent in certain central Asian and southern African strains of Cannabis.