Taxadienone
| Names | |
|---|---|
| IUPAC name
Taxa-4,11-dien-2-one
| |
| Systematic IUPAC name
(4aS,6R,12aS)-4,9,12a,13,13-Pentamethyl-2,4a,6,7,8,11,12,12a-octahydro-6,10-methanobenzo[10]annulen-5(1H)-one | |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
CompTox Dashboard (EPA)
|
|
| |
| |
| Properties | |
| C20H30O | |
| Molar mass | 286.459 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
| |
Taxadienone ((+)-taxa-4(5),11(12)-dien-2-one) is an organic compound and a taxane. The compound is of some academic interest as a potential precursor to Taxol, in important anti-cancer drug, in a commercially viable process. A total synthesis of taxadienone was reported in 2012 together with its conversion to the next Taxol precursor taxadiene. A multigram synthetic method was reported in 2015.