List of tallest buildings in Jacksonville

Jacksonville is the most populous city in the U.S. state of Florida, while its metropolitan area is the fourth-largest in the state, with 1.76 million inhabitants. The city is home to 23 buildings that stand over 200 feet (61 m) tall as of 2026, nine of which exceed 300 feet (91 m) in height. Two skyscrapers reach a height of 492 ft (150 m), the most of any city in Florida outside the Miami and Tampa metropolitan areas. The tallest building in Jacksonville is the Bank of America Tower, which is 617 feet (188 m) tall and was built in 1990. The second tallest building in Jacksonville is the 535 ft (163 m) tall 1 Independent Square, which was formerly the city's tallest building from 1974 to 1990.

The earliest high-rises in Jacksonville appeared in the early 20th century. The city's first skyscraper is variously considered to be 121 Atlantic Place or the Bisbee Building; both buildings were completed in 1909. The Bisbee Building and the 11-story Florida Life Building, built in 1911, were part of the Laura Street Trio, a group of three buildings constructed in the wake of the city's Great Fire of 1901. The Florida Life Building was followed by the 15-story Heard National Bank Building in 1913; both buildings held the title of Florida's tallest building. In the 1920s, a construction boom led to the addition of the Barnett National Bank Building and 11 East Forsyth, the city's first buildings taller than 200 ft (61 m), in 1926.

After a lull in skyscraper development in the 1930s and 1940s following the onset of the Great Depression, high-rise construction resumed. One Prudential Plaza was built in 1954, reaching 309 ft (94 m) in height. It was overtaken by the 432 ft (132 m) Riverplace Tower, then the world's tallest precast, post-tensioned concrete structure, in 1967. 1 Independent Square, built in 1974, was the last building in Jacksonville to hold the title of Florida's tallest building, which it lost to One Tampa City Center in 1981. In the 2000s, residential condominium towers such as The Peninsula were added to the downtown skyline. Since the Great Recession, few tall buildings have been constructed in Jacksonville, leaving the skyline relatively unchanged from the late 2000s.

Most of the city's tallest buildings are located in Downtown Jacksonville, which is bisected by the St. Johns River. The downtown core is north of the river and has a greater concentration of high-rises, including the city's two tallest skyscrapers. The tallest building in Southbank, the section of downtown south of the river, is The Peninsula, followed by Riverplace Tower. Besides its high-rises, the Main Street Bridge, nicknamed the 'Blue Bridge' for its color, is one of the skyline's most recognizable features.