| toc1
|
| Gene
|
| Number of Exons |
6
|
| Number of Introns |
5
|
| Size |
3.49 kb
|
| mRNA
|
| size |
2713 bp
|
| Protein
|
| Molecular Weight |
69.2 kDa
|
| pI |
7.5
|
| Amino Acids |
618
|
| Location in Arabidopsis
|
| Chromosome |
5
|
| Distance |
79.0 cM
|
| Locus Tag |
AT5G61380
|
Timing of CAB expression 1 is a protein that in Arabidopsis thaliana is encoded by the TOC1 gene. TOC1 is also known as two-component response regulator-like APRR1.
TOC1 was the first plant gene that, when mutated, yielded a circadian phenotype. It codes for the transcription factor TOC1, which affects the period of plants' circadian rhythms: built-in, malleable oscillations that repeat every 24 hours. The gene codes for a transcriptional repressor, TOC1, one of five pseudo-response regulators (PRR) that mediate the period of the circadian clock in plants. The TOC1 protein is involved in the clock's evening loop, which is a repressilator that directly inhibits transcription of morning loop genes LHY and CCA1. Toc1 gene is expressed in most plant structures and cells, and has its locus on chromosome 5.