TMEM273


TMEM273
Identifiers
AliasesTMEM273, chromosome 10 open reading frame 128, C10orf128, transmembrane protein 273
External IDsMGI: 1916319; HomoloGene: 78635; GeneCards: TMEM273; OMA:TMEM273 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

170371

69069

Ensembl

ENSG00000204161

ENSMUSG00000041707

UniProt

Q5T292
Q5T290

E9PVZ2

RefSeq (mRNA)

NM_001163616

RefSeq (protein)

NP_001157088

Location (UCSC)Chr 10: 49.15 – 49.19 MbChr 14: 32.51 – 32.54 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane protein 273 (TMEM273) aka C10orf128, is a protein which in humans is encoded by the TMEM273 gene. This protein is found within the topological domain as TMEM273 is a single-pass type I membrane protein. Although the function TMEM273 is relatively novel within the scientific community, existing research has shown that the protein may mediate histone trimethylation modifications, immunosuppression, and macrophage chemotaxis inhibition. TMEM273 expression is ubiquitous and is associated with various diseases and illnesses. Recent studies have revealed likely links to lung adenocarcinomas and acute myeloid leukemia