TLE4

TLE4
Identifiers
Aliases	TLE4, BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, transducin like enhancer of split 4, TLE family member 4, transcriptional corepressor, E(spl)
External IDs	OMIM: 605132; MGI: 104633; HomoloGene: 38259; GeneCards: TLE4; OMA:TLE4 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	79,726,882 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	14,575,415 bp
RNA expression pattern
	Top expressed in
	optic nerve; ; left testis; ; right testis; ; endothelial cell; ; corpus callosum; ; inferior olivary nucleus; ; inferior ganglion of vagus nerve; ; dorsal motor nucleus of vagus nerve; ; Region I of hippocampus proper; ; bone marrow cell;
	Top expressed in
	renal corpuscle; ; medullary collecting duct; ; vestibular membrane of cochlear duct; ; superior cervical ganglion; ; suprachiasmatic nucleus; ; conjunctival fornix; ; nucleus accumbens; ; retinal pigment epithelium; ; tail of embryo; ; olfactory tubercle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; chromatin binding; protein binding; transcription corepressor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; molecular function;
Cellular component	nucleus; nucleoplasm; transcription regulator complex; beta-catenin-TCF complex;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; Wnt signaling pathway; transcription, DNA-templated; beta-catenin-TCF complex assembly; cellular response to leukemia inhibitory factor; biological process; negative regulation of canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7091
	21888
	ENSG00000106829
	ENSMUSG00000024642
	Q04727
	Q62441
NM_001282748; NM_001282749; NM_001282753; NM_001282760; NM_007005;
	NM_001351541; NM_001351542; NM_001351543; NM_001351546; NM_001351547; NM_001351550; NM_001351552; NM_001351558; NM_001351560; NM_001351562; NM_001351563; NM_001351564; NM_001351556
	NM_011600; NM_001302947; NM_001302950; NM_001302951
NP_001269677; NP_001269678; NP_001269682; NP_001269689; NP_008936;
	NP_001338470; NP_001338471; NP_001338472; NP_001338475; NP_001338476; NP_001338479; NP_001338481; NP_001338487; NP_001338489; NP_001338491; NP_001338492; NP_001338493; NP_001338485
	NP_001289876; NP_001289879; NP_001289880; NP_035730
	Wikidata
View/Edit Human	View/Edit Mouse

Transducin-like enhancer protein 4 is a protein that in humans is encoded by the TLE4 gene.