TFAP2C

TFAP2C
Identifiers
Aliases	TFAP2C, AP2-GAMMA, ERF1, TFAP2G, hAP-2g, transcription factor AP-2 gamma
External IDs	OMIM: 601602; MGI: 106032; HomoloGene: 2423; GeneCards: TFAP2C; OMA:TFAP2C - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	56,639,283 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	172,400,542 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; epithelium of lactiferous gland; ; lactiferous duct; ; skin of thigh; ; vulva; ; skin of hip; ; gingival epithelium; ; hair follicle; ; skin of arm; ; buccal mucosa cell;
	Top expressed in
	conjunctival fornix; ; hair follicle; ; decidua; ; otic placode; ; gastrula; ; maxillary prominence; ; ventricular zone; ; primitive streak; ; condyle; ; lactiferous gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding; protein dimerization activity; DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	mitochondrion; nucleus; nucleoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; cell-cell signaling; male gonad development; regulation of transcription, DNA-templated; regulation of cell population proliferation; regulation of gene expression, epigenetic; transcription, DNA-templated; transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7022
	21420
	ENSG00000087510
	ENSMUSG00000028640
	Q92754
	Q61312
	NM_003222
	NM_001159696; NM_009335
	NP_003213
	NP_001153168; NP_033361
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor AP-2 gamma also known as AP2-gamma is a protein that in humans is encoded by the TFAP2C gene. AP2-gamma is a member of the activating protein 2 family of transcription factors.