5,6-Dihydro-5(α-thyminyl)thymine

5,6-Dihydro-5(α-thyminyl)thymine
Names
Preferred IUPAC name
5-[(5-Methyl-2,4-dioxo-1,3-diazinan-5-yl)methyl]pyrimidine-2,4(1H,3H)-dione
Other names
5-Thyminyl-5,6-dihydrothymine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C10H12N4O4/c1-10(4-12-9(18)14-7(10)16)2-5-3-11-8(17)13-6(5)15/h3H,2,4H2,1H3,(H2,11,13,15,17)(H2,12,14,16,18)
    Key: RQDDFAKFBFKUBC-UHFFFAOYSA-N
  • CC1(CNC(=O)NC1=O)CC2=CNC(=O)NC2=O
Properties
C10H12N4O4
Molar mass 252.230 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

5,6-Dihydro-5(α-thyminyl)thymine is a DNA pyrimidine dimer photoproduct produced when DNA in bacterial spores is exposed to ultraviolet light. In bacteria, this DNA base dimer deforms the structure of DNA, so endospore forming bacteria have an enzyme called spore photoproduct lyase that repairs this damage.

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