Spartanburg County, South Carolina

Spartanburg County, South Carolina
Spartanburg County Courthouse
Location within the U.S. state of South Carolina
Coordinates: 34°56′N 81°59′W / 34.93°N 81.99°W / 34.93; -81.99
Country United States
State South Carolina
Founded1791
Named afterSpartan Regiment
SeatSpartanburg
Largest communitySpartanburg
Area
 • Total
819.74 sq mi (2,123.1 km2)
 • Land808.34 sq mi (2,093.6 km2)
 • Water11.40 sq mi (29.5 km2)  1.39%
Population
 (2020)
 • Total
327,997
 • Estimate 
(2024)
369,256
 • Density405.77/sq mi (156.67/km2)
Time zoneUTC−5 (Eastern)
 • Summer (DST)UTC−4 (EDT)
Congressional districts4th, 5th
Websitewww.spartanburgcounty.org

Spartanburg County is a county located on the northwestern border of the U.S. state of South Carolina. As of the 2020 census, the population was 327,997, making it the fifth-most populous county in South Carolina. Its county seat is Spartanburg. Spartanburg County is the largest county within the Spartanburg, SC Metropolitan Statistical Area, which is also included in the Greenville-Spartanburg-Anderson, SC Combined Statistical Area.

In 2026, Spartanburg was ground zero for the largest measles outbreak since 2000, the year in which measles were declared eliminated in the United States. The county is characterized by low vaccination rates among children and extensive vaccine skepticism.