Spana Prosecution
The Spana Prosecution was a major criminal case which took place in Rome in the Papal States between January 1659 and March 1660.
The Papal authorities under the leadership of lieutenant governor Stefano Bracchi investigated a case involving a criminal net of poisoners, mainly women, for selling the famous poison Aqua Tofana to clients who wished to commit murder, in particular women who wished to become widows. The process involved over forty people, including professional poisoners and clients, some of them members of the aristocracy, and resulted in punishment ranging from exile and lifetime house arrest to the execution of five main figures, among them the central figure Gironima Spana.