Spätzle (protein)

Spätzle (protein)
Identifiers
OrganismDrosophila melanogaster
Symbolspz
UniProtP48607
Search for
StructuresSwiss-model
DomainsInterPro
Spätzle
Identifiers
SymbolSpaetzle
PfamPF16077
InterProIPR032104
Available protein structures:
PDB  IPR032104 PF16077 (ECOD; PDBsum)  
AlphaFold

Spätzle or spaetzle (German for a type of noodle) is an evolutionarily-conserved arthropod protein first identified in Drosophila melanogaster. It plays a role in embryonic development and in the insect innate immune response. The name was coined by the Nobel laureate Christiane Nüsslein-Volhard after the Spätzle noodle-like form of homozygous mutant fly larvae.