South San Francisco, California

South San Francisco, California
South San Francisco as viewed from Sweeney Ridge
Nicknames: 
South City; The Industrial City; The Birthplace of Biotechnology
Location in San Mateo County and the state of California
South San Francisco, California
Location in the United States
Coordinates: 37°39′N 122°25′W / 37.650°N 122.417°W / 37.650; -122.417
CountryUnited States
StateCalifornia
CountySan Mateo
CSASan Jose–San Francisco–Oakland
MetroSan Francisco–Oakland–Hayward
IncorporatedSeptember 19, 1908
Government
 • MayorMark Addiego
 • Vice MayorMark Nagales
 • City ManagerSharon Ranals
 • CouncilmembersJames H. Coleman
Eddie Flores
Buenaflor Nicolas
Area
 • City
30.17 sq mi (78.15 km2)
 • Land9.20 sq mi (23.84 km2)
 • Water20.97 sq mi (54.32 km2)  69.50%
Elevation
16 ft (5 m)
Population
 (2020)
 • City
66,105
 • Density7,183/sq mi (2,773.4/km2)
 • Metro
4,749,008 (13th)
 • CSA
9,714,023 (5th)
DemonymSouth San Franciscan
Time zoneUTC−8 (Pacific Time Zone)
 • Summer (DST)UTC−7 (PDT)
ZIP Codes
94080, 94083, 94099
Area code650
FIPS code06-73262
GNIS feature IDs277618, 2411942
Websitewww.ssf.net

South San Francisco is a city in San Mateo County, California, United States, on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially termed "South City". The population was 66,105 at the 2020 census.