Sjögren's disease

Not to be confused with Sjögren–Larsson syndrome and Marinesco–Sjögren syndrome.

Sjögren's disease
Image with a microscope of focal lymphoid infiltration in the minor salivary gland associated with Sjögren's disease
Pronunciation
  • UK: /ˈʃɜːɡrɛn/, US: /ˈʃoʊɡrɛn/
    Swedish: [ˈɧø̂ːɡreːn]
SpecialtyImmunology, rheumatology 
SymptomsDry mouth, dry eyes, other areas of dryness, major fatigue, joint pain, brain fog
ComplicationsLymphoma, Peripheral neuropathy, Dysautonomia
Usual onsetMiddle age or earlier
DurationLong term
CausesAutoimmune disease (unknown cause)
Diagnostic methodTissue biopsy, blood tests
Differential diagnosisMedication side effect, anxiety, sarcoidosis, amyloidosis
TreatmentHydroxychloroquine, Artificial tears, medications to reduce inflammation
PrognosisNormal life expectancy
Frequency~0.7%

Sjögren's disease (SjD), previously known as Sjögren syndrome or Sjögren's syndrome (SjS, SS), is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the lacrimal and salivary glands. Common symptoms include dry mouth and dry eyes, and it often seriously affects other organ systems, such as the lungs, kidneys, and nervous system.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.