STX16

STX16
Identifiers
Aliases	STX16, SYN16, syntaxin 16, SYN-16
External IDs	OMIM: 603666; MGI: 1923396; HomoloGene: 2791; GeneCards: STX16; OMA:STX16 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	58,679,526 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	173,941,564 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; sural nerve; ; corpus callosum; ; superficial temporal artery; ; pituitary gland; ; right hemisphere of cerebellum; ; body of uterus; ; C1 segment; ; right ovary; ; anterior pituitary;
	Top expressed in
	hand; ; neural layer of retina; ; otolith organ; ; utricle; ; thymus; ; lens; ; cerebellar cortex; ; primary visual cortex; ; yolk sac; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	SNAP receptor activity; protein binding; syntaxin binding; SNARE binding;
Cellular component	cytoplasm; integral component of membrane; Golgi apparatus; membrane; intracellular membrane-bounded organelle; Golgi cisterna; focal adhesion; trans-Golgi network; SNARE complex; endoplasmic reticulum; perinuclear region of cytoplasm; cytosol; trans-Golgi network membrane; Golgi membrane; endomembrane system; integral component of synaptic vesicle membrane;
Biological process	vesicle docking; retrograde transport, endosome to Golgi; protein transport; intracellular protein transport; vesicle fusion; Golgi ribbon formation; vesicle-mediated transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	8675
	228960
	ENSG00000124222
	ENSMUSG00000027522
	O14662
	Q8BVI5
NM_001001433; NM_001001434; NM_001134772; NM_001134773; NM_001204868;
	NM_003763
NM_001102423; NM_001102424; NM_001102425; NM_172675; NM_001363029;
	NM_001363030; NM_001363031
	NP_001001433; NP_001128244; NP_001128245; NP_001191797; NP_003754
NP_001095893; NP_001095894; NP_001095895; NP_766263; NP_001349958;
	NP_001349959; NP_001349960
	Wikidata
View/Edit Human	View/Edit Mouse

Syntaxin-16 (STX16) is a part of a protein family group called SNARE proteins (soluble N-ethylmaleimide-sensitive factor attachment proteins). SNARE proteins can generally be classified into two types: v-SNAREs(vesicle-SNAREs), which are embedded in the membranes of transport vesicles as they form, and t-SNAREs (target-SNAREs), which are located on the target membranes, such as those found at nerve terminals. STX16 is considered to be a t-SNARE, making it a key protein that makes membrane fusion happen.