STRA8

STRA8
Identifiers
Aliases	STRA8, stimulated by retinoic acid 8
External IDs	OMIM: 609987; MGI: 107917; HomoloGene: 49197; GeneCards: STRA8; OMA:STRA8 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	135,258,663 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	34,916,279 bp
RNA expression pattern
	Top expressed in
	gonad; ; sural nerve; ; human kidney; ; placenta; ; right testis; ; renal cortex; ; left testis; ; skin of abdomen; ; left uterine tube; ; putamen;
	Top expressed in
	spermatogonium; ; seminiferous tubule; ; blastocyst; ; spermatid; ; trophoblast giant cell; ; embryo; ; morula; ; spermatocyte; ; embryo; ; greater petrosal nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein dimerization activity;
Cellular component	cytoplasm; nucleus;
Biological process	DNA replication; cellular response to retinoic acid; meiosis; spermatogenesis; regulation of transcription, DNA-templated; male germ-line stem cell asymmetric division; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; oogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	346673
	20899
	ENSG00000146857
	ENSMUSG00000029848
	Q7Z7C7
	P70278
	NM_182489; NM_001394401
	NM_009292
	NP_872295
	NP_033318
	Wikidata
View/Edit Human	View/Edit Mouse

Stimulated by retinoic acid 8 is a protein that in humans is encoded by the STRA8 gene.

STRA8 is activated only upon stimulation by retinoic acid and expresses a cytoplasmic protein in the gonads of male and female vertebrates. It plays a key role in gametogenesis by inducing meiosis.