Receptor protein serine/threonine kinase

Receptor protein serine/threonine kinase
Identifiers
SymbolReceptor protein serine/threonine kinase
Membranome1031
Receptor protein serine/threonine kinase
Identifiers
EC no.2.7.11.30
CAS no.146702-86-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Receptor protein serine/threonine kinases (EC 2.7.11.30) are enzyme-linked receptors that belong to protein-serine/threonine kinases. The systematic name of this enzyme class is ATP:[receptor-protein] phosphotransferase. Proteins from this group participate in numerous biological pathways, processes and diseases including MAPK signaling pathway, cytokine-cytokine receptor interactions, TGF beta signaling pathway, colorectal cancer, pancreatic cancer, and chronic myeloid leukemia.

Receptor serine/threonine kinases directly phosphorylate specific serines or threonines on themselves and on other regulatory proteins.